Keynote Speakers

Ryan D. Roberts, MD, PhD

Narrowing focus, expanding impact:  How a deep dive into the metastatic niche can improve care for kids and dogs fighting cancer

Date/Time: Thursday, October 17 – 1:15 p.m.

Synopsis:  Using murine models of metastasis, tumor-on-lung organoid systems, single-cell analytical systems, and conventional cell biology, our team has identified tumor-host signaling interactions critical to metastasis development in the lung. Our discoveries show that disseminated tumor cells exhibit divergent phenotypes that can cooperate to manipulate the behavior of lung tissues in ways that facilitate the establishment and growth of metastatic lesions. Active research projects include the pre-clinical validation of candidate therapies, development of both human and canine integrative clinical trials, elucidation of tumor-lung signaling pathways that drive metastasis in osteosarcoma, and identification of ways in which tumor cells cooperate with each other to drive malignant progression.

About the presenter:  Ryan D. Roberts, MD, PhD, is a physician for the Division of Hematology and Oncology at Nationwide Children’s Hospital, a principal investigator for the Center for Childhood Cancer at The Research Institute at Nationwide Children’s Hospital and a member of the Translational Therapeutics research program at The James Comprehensive Cancer Center at The Ohio State University.

Dr. Roberts is a graduate of the Medical Scientist Training Program at the Ohio State University and of the Pediatrics Residency and Pediatric Hematology, Oncology, and BMT Fellowship at Nationwide Children’s Hospital. In 2016, he joined the faculty of the Research Institute at Nationwide Children’s Hospital, building on the research program that he developed as a resident and fellow.

Sponsored by:

Shruthi Naik, PhD

Oncolytic virus therapy for canine cancer

Date/Time: Saturday, October 19 – 8:30 a.m.

About the presenter:  Dr. Naik is an investigator in the Department of Molecular Medicine at Mayo Clinic and co-founder of Vyriad. Her goal is to bridge the gap between research and clinical translation to deliver new technologies to patients in need. Her research focuses on development and clinical translation of novel oncolytic virus therapies She has led studies to evaluate systemic oncolytic virus therapy to treat canine cancer and guide development of these novel treatments for human malignancies. 

Sponsored by: