Resident Review Workshop

Thursday, October 13th     8:00 am – 12:00 pm

This workshop is sponsored by


 

Speaker #1:  Dr. Cheryl London, Tufts University

Presentation Topic:  Review of immuno-oncology: Current advances and remaining challenges 

Speaker Notes:  Click HERE
Speaker notes will NOT be available onsite.  Download and print a copy for your use on site.

Time:  8:00 am – 9:45 am

Presentation Synopsis:  Over the past two decades, substantial advances in our understanding of the immune system have helped better define the nature of immune dysfunction in the context of cancer.  These have facilitated the development of novel treatment interventions designed to target immune cells, tumor cells, and other components of the tumor microenvironment to induce tumor regression.  Perhaps the largest impact has been in the setting of immune checkpoint inhibitors, alone or in combination with other treatment modalities.  Despite this, substantial challenges remain as most cancer patients do not experience benefit from immunotherapy.  This review session will cover basic aspects of normal immune function,  landscape of dysfunction in the setting of cancer, current and future immunotherapeutic approaches, and advances in immunotherapy for veterinary cancer patients.

About the Presenter:  Cheryl London, DVM, PhD, ACVIM (Oncology) is a Research Professor at Cummings School of Veterinary Medicine at Tufts University and the Molecular Oncology Research Institute at Tufts Medical Center. She has an active laboratory research program centered on comparative and translational oncology and is involved in the training of graduate students and postdoctoral fellows. She has recently joined the Clinical Trials Office at Cummings School to expand operations and enhance capacity and breadth of trials performed in client owned animals. Dr. London is also an Associate Faculty Professor at the Ohio State University College of Veterinary Medicine (OSU CVM) where she remains Director of the Clinical Trials Office at the CVM and Director of Translational Therapeutics at the Center for Clinical and Translational Sciences, OSU College of Medicine. Prior to her time at OSU, she was an Assistant Professor in the Department of Surgical and Radiological Sciences at the University of California, Davis.

 


Speaker #1:  Dr. Jenna Burton, Colorado State University

Presentation Title: Cancer clinical trials: The basics of design, conduct, and application in veterinary oncology

Speaker Notes:  Click HERE
Speaker notes will NOT be available onsite.  Download and print a copy for your use on site.

Time:  10:15 am – 12:00 pm

Presentation Synopsis:  Clinical trials are prospective research studies conducted to assess the efficacy and benefit of new drugs, treatment protocols, surgical interventions, and diagnostic techniques. Development and implementation of well-designed clinical trials serve to advance our knowledge of tumor pathobiology, guide drug development, and are paramount to advance the practice of Evidence-Based Medicine to inform treatment recommendations for veterinary patients with cancer. This lecture will provide an overview on commonly used clinical trials designs used in veterinary and comparative oncology, as well as discuss critical components of clinical trial conduct, including protocol development, Good Clinical Practice (GCP), owner informed consent, and adverse event assessment. Successes and challenges of veterinary oncology clinical trials will be highlighted using examples from published veterinary literature.

About the Presenter:  Jenna Burton, DVM, MS, ACVIM (Oncology) attended veterinary school at The Ohio State University then joined the team at the Flint Animal Cancer Center at Colorado State University (CSU) as an intern, medical oncology resident, and finally as a faculty member.  Following her stint at CSU, Dr. Burton joined the faculty of the University of California, Davis where she served as the director of the Veterinary Center for Clinical Trials.  She returned to CSU in 2020 and is currently an Associate Professor in the Flint Animal Cancer Center.  Her research is focused on the conduct of clinical trials to improve the health and treatment of pets with cancer, with an emphasis on comparative oncology trials. “The science of cancer and cancer treatment is evolving at an incredibly rapid pace, and it is rewarding to be involved with research that could improve the lives of all patients with cancer. It is meaningful to me to feel as though I am contributing to the greater good – I truly believe the steps we take forward in veterinary oncology can eventually help all patients, human or animal, with cancer.”